BDBM4202 6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido[2,3-d]pyrimidin-7(8H)-one deriv. 6d

SMILES CCN(CC)CCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1

InChI Key InChIKey=UJWFQKNVQJGDQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4202   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4202BDBM4202(6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4202BDBM4202(6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4202BDBM4202(6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed