BDBM42539 4-(Hydroxy-diphenyl-methyl)-piperidine-1-carbothioic acid (4-ethoxy-phenyl)-amide::4-[hydroxy(diphenyl)methyl]-N-p-phenetyl-piperidine-1-carbothioamide::MLS000569101::N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide::N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide::N-(4-ethoxyphenyl)-4-[oxidanyl(diphenyl)methyl]piperidine-1-carbothioamide::SMR000177227::cid_2936384

SMILES CCOc1ccc(NC(=S)N2CCC(CC2)C(O)(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=PMEQBGAGFZDWQX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 42539   

TargetNeuropeptide Y receptor type 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 42539BDBM42539(N-(4-ethoxyphenyl)-4-[oxidanyl(diphenyl)methyl]pip...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at NPYY2 receptor (unknown origin) by cAMP biosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 42539BDBM42539(N-(4-ethoxyphenyl)-4-[oxidanyl(diphenyl)methyl]pip...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at neuropeptide Y receptor Y2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 42539BDBM42539(N-(4-ethoxyphenyl)-4-[oxidanyl(diphenyl)methyl]pip...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed