BDBM429990 N-[(1R)-2-({4-[N-(3-cyano-4- fluorophenyl)-N'- hydroxycarbamimidoyl]-1,2,5- oxadiazol-3-yl}sulfanyl)-1- methylethyl]acetamide::US10538497, Example 179

SMILES C[C@H](CSc1nonc1\C(Nc1ccc(F)c(c1)C#N)=N\O)NC(C)=O

InChI Key InChIKey=HNTDMMWORISOKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429990   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429990(US10538497, Example 179 | N-[(1R)-2-({4-[N-(3-cyan...)
Affinity DataIC50: 218nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent