BDBM452916 7-amino-5-methyl-3- [[3-[(1S,5S,6R)-3- phenyl-6-bicyclo [3.1.0]hex-2-enyl]- 1,2,4-oxadiazol-5-yl] methyl]pyrido[2,3-d] pyrimidin-4-one::US10711004, Example 238

SMILES Cc1cc(N)nc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccccc3)c(=O)c12

InChI Key InChIKey=JWNCZSYHJIVUEU-GUXCAODWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452916   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452916(7-amino-5-methyl-3- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50:  1.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452916(7-amino-5-methyl-3- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50:  11.3nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent