BDBM478628 1-{4-[(1R or 1S)-1-(2-{[6-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-benzimidazol-2-yl]amino}pyridin-4-yl)ethyl]piperazin-1-yl}-3,3,3-trifluoropropan-1-one::US10894784, Example 89.02

SMILES CC(N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cc(C)nn2C)c1

InChI Key InChIKey=RXVPTRMSIDASEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478628   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478628(US10894784, Example 89.02 | 1-{4-[(1R or 1S)-1-(2-...)
Affinity DataIC50: 450nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent