BDBM50015377 CHEMBL3264605
SMILES CC(C)C(O)(c1c[nH]nn1)c1ccc2cc(OC(F)F)c(OC(F)F)cc2c1
InChI Key InChIKey=ZBRAJOQFSNYJMF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50015377
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Viamet Pharmaceuticals
Curated by ChEMBL
Viamet Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Viamet Pharmaceuticals
Curated by ChEMBL
Viamet Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair