BDBM50016086 4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-6,14-dione(Ketonaltrexone)::CHEMBL366520

SMILES Oc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)C(N(CC5CC5)CCC314)C2=O

InChI Key InChIKey=MLHMRULRADVYER-ZUPWUQBJSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016086   

TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50016086(4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-o...)
Affinity DataKi:  31nMAssay Description:Inhibitory binding constant in guinea pig brain homogenate was reported at mu site at a temperature 25 degree Centigrade labeled with [3H](D-Ala2-MeP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50016086(4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-o...)
Affinity DataKi:  102nMAssay Description:Inhibitory binding constant in guinea pig brain homogenate was reported at Opioid receptor kappa 1 at temperature 25 degree Celsius labeled with (-)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50016086(4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-o...)
Affinity DataKi:  281nMAssay Description:Inhibitory binding constant in guinea pig brain homogenate was reported at Opioid receptor delta 1 at a temperature 25 degree Celsius labeled with [3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed