BDBM50016999 7-Chloro-2-(4-methoxy-benzyl)-3-methyl-benzofuran-4-ol::CHEMBL280281

SMILES COc1ccc(Cc2oc3c(Cl)ccc(O)c3c2C)cc1

InChI Key InChIKey=BNMUOPQIDQSEFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016999   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016999(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-benzofuran-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016999(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-benzofuran-...)
Affinity DataIC50:  376nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed