BDBM50018155 8-Phenyl-3-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL20806

SMILES CCCn1c2nc([nH]c2c(=O)[nH]c1=O)-c1ccccc1

InChI Key InChIKey=IFTBXZYFIQVMHB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018155   

TargetAdenosine receptor A1(Rat)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50018155(CHEMBL20806 | 8-Phenyl-3-propyl-3,7-dihydro-purine...)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50018155(CHEMBL20806 | 8-Phenyl-3-propyl-3,7-dihydro-purine...)
Affinity DataKi:  9.80E+3nMAssay Description:Binding affinity at A1 adenosine receptor in rat brain cortical membrane using [3H]- N6-R-phenylisopropyladenosine (R-PIA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50018155(CHEMBL20806 | 8-Phenyl-3-propyl-3,7-dihydro-purine...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50018155(CHEMBL20806 | 8-Phenyl-3-propyl-3,7-dihydro-purine...)
Affinity DataKi:  6.10E+4nMAssay Description:Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed