BDBM50018617 6-(4-Imidazol-1-yl-phenyl)-2H-pyridazin-3-one::CHEMBL287398

SMILES O=c1ccc(n[nH]1)-c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=NCNPWWDCUPUDBU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50018617   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of cAMP PDE III enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018617(CHEMBL287398 | 6-(4-Imidazol-1-yl-phenyl)-2H-pyrid...)
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed