BDBM50019484 CHEMBL384584::NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH

SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O

InChI Key InChIKey=WZHQALIQGVYQGG-DTQUPHKSSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50019484   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataKi:  0.0320nMAssay Description:Compound was evaluated for the inhibition of [3H]-bremazocine binding to Opioid receptor kappa 1 in guinea pig cerebellum membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for the inhibition of [3H]DAGO([[3H]-D-Ala,MePhe4,Glyol5]enkephalin) binding to mu sites in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for the inhibition of [3H]DSLET([[3H]-D-Ser2,Leu5,Thr6]enkephalin binding to Opioid receptor delta 1 in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataIC50:  929nMAssay Description:Compound was evaluated for the agonistic activity against Opioid receptor delta 1 in hamster vas deferens.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataIC50:  3.30nMAssay Description:Compound was evaluated for the agonistic activity against Opioid receptor mu 1 in guinea pig ileum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019484(CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...)
Affinity DataIC50:  12nMAssay Description:Compound was evaluated for the agonistic activity against Opioid receptor kappa 1 in rabbit vas deferens.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed