BDBM50022188 7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid::CHEMBL12567

SMILES COc1ccc2c(cc(=O)oc2c1)C(O)=O

InChI Key InChIKey=IHHLDCASADSHEG-UHFFFAOYSA-N

Data  13 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50022188   

TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  45nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  3.72E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15(Mus musculus)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  2.68E+4nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  2.74E+4nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  3.01E+4nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi:  4.95E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataIC50:  1.10E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed