BDBM50022851 CHEMBL413534::Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=XPAHSKSBHMOJNZ-DIAUVYRXSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50022851   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  9.41E+3nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  9.40E+3nMAssay Description:Compound was tested for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  1.20E+4nMAssay Description:Compound was tested for inhibition of Angiotensin I converting enzyme from rabbit lung.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity was evaluated against Angiotensin I converting enzyme activity in rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed