BDBM50025079 CHEMBL30344::[4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amine

SMILES CC(N)Cc1ccc(cc1C)N(C)C

InChI Key InChIKey=HFQMYSHATTXRTC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025079   

LigandPNGBDBM50025079([4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amin...)
Affinity DataIC50: 100nMAssay Description:Compound was tested in vitro for inhibition of Serotonin transporter uptake at serotonin uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025079([4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amin...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of NE uptake at NE uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025079([4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amin...)
Affinity DataIC50: 800nMAssay Description:Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025079([4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amin...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo inhibition of DA uptake at dopamine uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025079([4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amin...)
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was tested in vitro for inhibition of MAO by using [14C]phenylethylamine as substrate in rat brain mitochondrial preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed