BDBM50025405 10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenanthrene-3,17-dione::CHEMBL1230438

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CCC2=O

InChI Key InChIKey=RAJWOBJTTGJROA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025405   

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025405BDBM50025405(10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenant...)
Affinity DataIC50: 20nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025405BDBM50025405(10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenant...)
Affinity DataIC50: 390nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025405BDBM50025405(10,13-Dimethyl-tetradecahydro-cyclopenta[a]phenant...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed