BDBM50025972 7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carboxylic acid::CHEMBL422920

SMILES OC(=O)C1=CC(=O)C2=CCC(=O)CC2O1

InChI Key InChIKey=JOPBDABTROBTFI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025972   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025972(7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carbox...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025972(7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carbox...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025972(7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carbox...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025972(7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carbox...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025972(7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carbox...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed