BDBM50029459 CHEMBL3343420

SMILES COC1=CC2C(C=C1OCCCN1CCOCC1)N=CN=C2Nc1ccc(NC(=O)c2ccccc2)cc1

InChI Key InChIKey=CJFROAYTGUAJIP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029459   

TargetAurora kinase A(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029459(CHEMBL3343420)
Affinity DataIC50:  138nMAssay Description:Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029459(CHEMBL3343420)
Affinity DataIC50:  130nMAssay Description:Inhibition of Aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029459(CHEMBL3343420)
Affinity DataIC50:  110nMAssay Description:Inhibition of Aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029459(CHEMBL3343420)
Affinity DataIC50:  156nMAssay Description:Inhibition of Aurora-B (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed