BDBM50035558 5-(2-Fluoro-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline::CHEMBL310238

SMILES Fc1ccccc1C1=Cc2ccccc2C2=NCCN12

InChI Key InChIKey=CRASKXTVWBAFRS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035558   

TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50035558(5-(2-Fluoro-phenyl)-2,3-dihydro-imidazo[2,1-a]isoq...)
Affinity DataIC50:  6.04E+3nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in global H3K27me3 level after 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50035558(5-(2-Fluoro-phenyl)-2,3-dihydro-imidazo[2,1-a]isoq...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of [3H]-PAF binding to human platelet activating factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed