BDBM50035886 CHEMBL3361065

SMILES CC(C)CN(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(NC2CCN(CC2)S(C)(=O)=O)nc1

InChI Key InChIKey=AUXZRHVPMQIECB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035886   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035886(CHEMBL3361065)
Affinity DataEC50:  520nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain expressed in bacterial expression system assessed as inhibition ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035886(CHEMBL3361065)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair