BDBM50041937 5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL321826

SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1

InChI Key InChIKey=UBEKRQCLVPLZMA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041937   

TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041937(5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...)
Affinity DataIC50: 1.90E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Beef liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041937(5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041937(5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041937(5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041937(5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed