BDBM50050793 3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL302564

SMILES COc1nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)nc2CCCc12

InChI Key InChIKey=HMBISNTYKZVPJD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050793   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  20.4nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  56nMAssay Description:Binding affinity of the compound towards Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed