BDBM50050809 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl-phenoxy)-3-phenyl-butyric acid methyl ester::CHEMBL67325

SMILES COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(Oc1ccc(cc1)C(C)C)c1ccccc1

InChI Key InChIKey=GJGNTDZVUULBFL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050809   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050809(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl...)
Affinity DataKi:  250nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050809(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed