BDBM50053262 CHEMBL3322935

SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(nn2)-c2cc(OC)cc(OC)c2)c1

InChI Key InChIKey=NAEAGLUMQZLQJC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50053262   

TargetAurora kinase A(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50053262(CHEMBL3322935)
Affinity DataIC50:  370nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50053262(CHEMBL3322935)
Affinity DataIC50:  768nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50053262(CHEMBL3322935)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50053262(CHEMBL3322935)
Affinity DataIC50:  3.58E+3nMAssay Description:Inhibition of Aurora B (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed