BDBM50058634 CHEMBL291840::N-[1-(2-furyl)ethyl]-N-hydroxyurea

SMILES CC(N(O)C(N)=O)c1ccco1

InChI Key InChIKey=YIBAXIRZUZKFMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058634   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058634(CHEMBL291840 | N-[1-(2-furyl)ethyl]-N-hydroxyurea)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058634(CHEMBL291840 | N-[1-(2-furyl)ethyl]-N-hydroxyurea)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed