BDBM50061168 CHEMBL3393706

SMILES Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(O[C@H]4CNCCC44CC4)n3)c2c1

InChI Key InChIKey=FCGLYPSBPNFQRF-FQEVSTJZSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061168   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed