BDBM50061458 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL63804

SMILES [#8-]-[n+]1ccc(-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2/c3ccc(Cl)cc3-[#6]-[#6]-c3cccnc-23)cc1

InChI Key InChIKey=SQAJXBGZLZTIBS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061458   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061458(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50:  530nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061458(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Farnesyl protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061458(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50:  530nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed