BDBM50064521 3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::3-[3,4-Dimethyl-1-(3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL51838

SMILES C[C@H]1CN(C\C=C\c2ccccc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=SUIRCGLIUIROIR-SRHFXGPLSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50064521   

TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  0.0390nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of binding of [3H]DAMGO to Opioid receptor mu 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  1nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by U69,593 to O...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  1.5nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by SMC-80 (Opio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  122nMAssay Description:Inhibition of binding of [3H]U69, 593 to Opioid receptor kappa 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  122nMAssay Description:Inhibition of [3H]U69,593 binding to Opioid receptor kappa 1 of guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  322nMAssay Description:Inhibition of binding of [3H]DADLE to Opioid receptor delta 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064521(3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  322nMAssay Description:Inhibition of [3H]-DADLE binding to Opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed