BDBM50065456 CHEMBL3402741

SMILES CCN(CC)CCCOC(=O)Nc1cccc(CN2N=C(CSC2=O)c2ccc(OC)c(OC)c2)c1

InChI Key InChIKey=WVYHFPSGWCCXMO-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065456   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50:  400nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065456(CHEMBL3402741)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair