BDBM50066288 2-(2-Hydroxy-benzoyl)-4-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-5-methyl-2,4-dihydro-pyrazol-3-one::CHEMBL325111

SMILES COc1cc(C=c2c(=C)[nH]n(C(=O)c3ccccc3O)c2=O)ccc1O

InChI Key InChIKey=CVAYRSRXMXOERL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066288   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066288(2-(2-Hydroxy-benzoyl)-4-[1-(4-hydroxy-3-methoxy-ph...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066288(2-(2-Hydroxy-benzoyl)-4-[1-(4-hydroxy-3-methoxy-ph...)
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed