BDBM50067447 3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL334898
SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1
InChI Key InChIKey=FJRARMQVERMSNJ-NWLLBJEDSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50067447
Affinity DataKi: 0.340nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding activity against kOpioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 272nMAssay Description:Binding activity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in rat brain membranes.More data for this Ligand-Target Pair