BDBM50069919 1-Benzyl-4-phenyl-piperazine::CHEMBL101032

SMILES C(N1CCN(CC1)c1ccccc1)c1ccccc1

InChI Key InChIKey=VEJWDLHOLWGRLH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50069919   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069919(1-Benzyl-4-phenyl-piperazine | CHEMBL101032)
Affinity DataKi:  16nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069919(1-Benzyl-4-phenyl-piperazine | CHEMBL101032)
Affinity DataKi:  124nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069919(1-Benzyl-4-phenyl-piperazine | CHEMBL101032)
Affinity DataKi:  267nMAssay Description:Binding affinity towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069919(1-Benzyl-4-phenyl-piperazine | CHEMBL101032)
Affinity DataKi: >300nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069919(1-Benzyl-4-phenyl-piperazine | CHEMBL101032)
Affinity DataKi: >400nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed