BDBM50074185 4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one::CHEMBL161969

SMILES O=C1CN(Cc2ccccc2)CCN1CCCc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=ZEUXWOAJQAVEPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074185   

Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074185(4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl...)
Affinity DataIC50: 173nMAssay Description:Displacement of [3H]5-HT binding to the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074185(4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl...)
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed