BDBM50075373 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)ethyl]phenyl}-4,5-dimethoxy-2-(3-quinolylcarboxamido)benzamide::CHEMBL348475::N-(2-((4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide::TARIQUIDAR::US11739089, Compound Tariquidar
SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cc(OC)c(OC)cc4NC(=O)c4cnc5ccccc5c4)cc3)Cc2cc1OC
InChI Key InChIKey=LGGHDPFKSSRQNS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50075373
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.46E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 5.24E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair