BDBM50075639 (E)-6-[3-(3-tert-Butyl-thioureido)-phenyl]-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL281338

SMILES CC(C)(C)NC(=S)Nc1cccc(c1)C(=CCCCC(O)=O)c1cccnc1

InChI Key InChIKey=RGGXEZXJJJANGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075639   

TargetThromboxane-A synthase(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075639((E)-6-[3-(3-tert-Butyl-thioureido)-phenyl]-6-pyrid...)
Affinity DataIC50: 22nMAssay Description:In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075639((E)-6-[3-(3-tert-Butyl-thioureido)-phenyl]-6-pyrid...)
Affinity DataIC50: 38nMAssay Description:In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed