BDBM50075640 6-{4-[2-cyano-1-cyclopropylamino-(E)-1-iminomethylamino]phenyl}-6-(3-pyridyl)-(E)-5-hexenoic acid::CHEMBL21849

SMILES OC(=O)CCCC=C(c1ccc(NC(NC2CC2)=NC#N)cc1)c1cccnc1

InChI Key InChIKey=BWTDHTXDACFICU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075640   

TargetThromboxane-A synthase(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075640(6-{4-[2-cyano-1-cyclopropylamino-(E)-1-iminomethyl...)
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075640(6-{4-[2-cyano-1-cyclopropylamino-(E)-1-iminomethyl...)
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed