BDBM50075776 4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-yl]-phenylamine::CHEMBL159163

SMILES Nc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=PLROHMUOLNMPBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075776   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075776(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50075776(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50075776(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed