BDBM50077411 (R)-2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::CHEMBL292226

SMILES CN(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)N2Cc3ccccc3C[C@@H]2C(=O)NO)cc1

InChI Key InChIKey=JXSWSZIEDSTKDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077411   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077411((R)-2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed