BDBM50080064 1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vinyl]-1H-[1,2,4]triazole::1-[2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vinyl]-1H-[1,2,4]triazole(Ro 64-5229)::CHEMBL305406

SMILES Clc1cccc(Cl)c1\C(OC1CCCCCC1)=C\n1cncn1

InChI Key InChIKey=STCVFKBRXOEQRF-YBEGLDIGSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080064   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataKi:  110nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataIC50:  500nMAssay Description:Inhibition of [3H]-DCG IV binding on rat mGluR2 transfected cell membranes from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50080064(1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of 10 uM 1S, 3R-ACPD stimulated GTP gamma 35S binding to rat mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed