BDBM50082481 CHEMBL141672::{2-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophene-2-sulfonyl]-1,2,3,4-tetrahydro-isoquinolin-3-yl}-oxo-acetic acid

SMILES CSc1nccc(n1)-c1ccc(s1)S(=O)(=O)N1Cc2ccccc2CC1C(=O)C(O)=O

InChI Key InChIKey=ULQUQVTVRZFECE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082481   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082481({2-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophene-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082481({2-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophene-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed