BDBM50085277 1-{2-[4-(Difluoro-phenyl-methyl)-phenoxy]-ethyl}-pyrrolidine::CHEMBL349189

SMILES FC(F)(c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=VKCDOYSPXISWTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085277   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085277(1-{2-[4-(Difluoro-phenyl-methyl)-phenoxy]-ethyl}-p...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085277(1-{2-[4-(Difluoro-phenyl-methyl)-phenoxy]-ethyl}-p...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed