BDBM50088394 2-(4-Dimethylamino-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL309106
SMILES CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3C(=O)N(C(=O)c3c2)c2ccc(cc2)N(C)C)CC1
InChI Key InChIKey=LQTJOPPTSIYEES-SANMLTNESA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50088394
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Binding affinity towards cloned human alpha-1A adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity of the compound towards recombinant human 5-hydroxytryptamine 7 receptor was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity of the compound towards recombinant human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Binding affinity of the compound towards recombinant human Dopamine receptor D2L was determined using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound towards recombinant human Dopamine receptor D2S was determined using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Binding affinity of the compound towards histamine H1 receptor was determined in guinea pig brain using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:Binding affinity towards cloned human alpha-1D adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Binding affinity of the compound towards recombinant human Dopamine receptor D3 was determined using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 169nMAssay Description:Binding affinity of the compound towards rat alpha-2B adrenergic receptor was determined using [3H]-yohimbine as radioligandMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity towards cloned human alpha-1B adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair