BDBM50091104 CHEMBL29422::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-acetamide

SMILES CC(=O)NCc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1

InChI Key InChIKey=XAHBFCGXCQNZHI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091104   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Human Endothelin A receptor expressed in CHO Cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibitory activity against human endothelin B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091104(CHEMBL29422 | N-[2'-(3,4-Dimethyl-isoxazol-5-ylsul...)
Affinity DataKi:  4.40E+3nMAssay Description:Inihibition of Human Endothelin B receptor expressed in CHO Cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed