BDBM50094693 8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::8-tert-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine::CHEMBL414620

SMILES CC(C)(C)n1cc2c(n1)nc(N)n1nc(nc21)-c1ccco1

InChI Key InChIKey=RWMLPEOKXLBPHX-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50094693   

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 36-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells; range 134-229More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]DPCPX from Adenosine A2b receptor expressed in CHO cells; range 343-468More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 1061-1245More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50094693(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4...)
Affinity DataKi:  1.15E+6nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed