BDBM50101080 2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl ester::CHEMBL45149

SMILES COC(=O)C(O)(O)C(=O)c1ccccc1

InChI Key InChIKey=QYHCWDVIEIXIRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101080   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed