BDBM50104982 CHEMBL175501::sodium salt of 4-tert-Butyl-N-{6-[2-(5-furan-2-yl-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-benzenesulfonamide

SMILES Cc1ccc(cc1)-c1c([N-]S(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCOc1ncc(cn1)-c1ccco1

InChI Key InChIKey=UJYIVMRMKFBTEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104982   

TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104982(CHEMBL175501 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.480nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104982(CHEMBL175501 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  7nMAssay Description:In vitro for specific binding of [125I]-ET-1 to GHcell expressed in Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed