BDBM50105081 8-[3-(4,5-Dimethoxy-2-nitro-phenyl)-acryloyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL324471

SMILES COc1cc(C=CC(=O)N2CCC3(CC2)N(CNC3=O)c2ccccc2)c(cc1OC)[N+]([O-])=O

InChI Key InChIKey=KQASXGJWNYGSNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105081   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105081(8-[3-(4,5-Dimethoxy-2-nitro-phenyl)-acryloyl]-1-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105081(8-[3-(4,5-Dimethoxy-2-nitro-phenyl)-acryloyl]-1-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105081(8-[3-(4,5-Dimethoxy-2-nitro-phenyl)-acryloyl]-1-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed