BDBM50108048 (E)-2-(3,5-dimethoxystyryl)thiophene::2-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene::2-[2-(3,5-Dimethoxy-phenyl)-vinyl]-thiophene::CHEMBL42428

SMILES COc1cc(OC)cc(\C=C\c2cccs2)c1

InChI Key InChIKey=URRYDXXEGGXDQJ-AATRIKPKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108048   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes expressing human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes expressing human cytochrome P450 1B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50108048((E)-2-(3,5-dimethoxystyryl)thiophene | 2-[(E)-2-(3...)
Affinity DataIC50:  61nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes epressing human cytochrome P450 1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed