BDBM50114750 3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcarboxamido]-2-phenyl-(1R)-ethylcarboxamido]-4-amino(imino)methylamino-(1S)-butylcarboxamido]-2-carbamoylethyl}-1H-indole::CHEMBL320157

SMILES CC(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=NSISWBCOSAKMBT-BPXGVECKSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50114750   

TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  4.25E+3nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  1.50E+4nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  684nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-5 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  1.50E+3nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-4 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 6 hrs by beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  680nMAssay Description:Agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 6 hrs by beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 6 hrs by beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50114750(3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcar...)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 6 hrs by beta-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed