BDBM50116515 CHEMBL3609729

SMILES Cc1sc(Nc2nccc(C)n2)nc1-c1cn[nH]c1

InChI Key InChIKey=MIQNXKWDQRNHAU-UHFFFAOYSA-N

Data  8 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50116515   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  9nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  52nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  52nMAssay Description:Positive allosteric modulation of mGluR4 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed