BDBM50117203 4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-N-pyridin-3-ylmethyl-benzamide::CB-30685::CHEMBL123446

SMILES C#CCN(Cc1cc2c(=O)[nH]c(C)nc2cc1Br)c1ccc(C(=O)NCc2cccnc2)cc1

InChI Key InChIKey=SHNBLWMBWXIKMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117203   

TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117203BDBM50117203(CB-30685 | 4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His-tagged human NAMPTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetThymidylate synthase(Human)
Myrexis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117203BDBM50117203(CB-30685 | 4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 156nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117203BDBM50117203(CB-30685 | 4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 156nMAssay Description:Growth inhibitory activity against mouse lymphoblastoid L1210TS cell line was determined as inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed